With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.652-39-1,4-Fluoroisobenzofuran-1,3-dione,as a common compound, the synthetic route is as follows.,652-39-1
General procedure: In a 25mL beaker, anhydride (1 mmol), semicarbazide (1mmol) were roughly mixed with montmorillonite K10 (1 g)and after 3 min of mechanical stirring, the mixture was irradiated into a single mode focused microwave reactor with continuous rotation.for18 min (optimized time) at 170 ¡ãC. Upon completion of the reaction, monitored on TLC (nhexane:ethyl acetate, 3:1), the product was extracted in dichloromethane(2 Chi 25 mL), solvent removal of the solid residue was crystallized from EtOH to yield compounds a-l.
652-39-1 4-Fluoroisobenzofuran-1,3-dione 69551, abenzofuran compound, is more and more widely used in various fields.
Reference£º
Article; Marvi, Omid; Nikpasand, Mohammad; Letters in Organic Chemistry; vol. 10; 5; (2013); p. 353 – 357;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem