Yoshimura, Masashi et al. published their research in Bioconjugate Chemistry in 2016 | CAS: 551001-79-7

(5-Methoxybenzofuran-2-yl)boronic acid (cas: 551001-79-7) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Recommanded Product: (5-Methoxybenzofuran-2-yl)boronic acid

Development of 99mTc-Labeled Pyridyl Benzofuran Derivatives To Detect Pancreatic Amylin in Islet Amyloid Model Mice was written by Yoshimura, Masashi;Ono, Masahiro;Watanabe, Hiroyuki;Kimura, Hiroyuki;Saji, Hideo. And the article was included in Bioconjugate Chemistry in 2016.Recommanded Product: (5-Methoxybenzofuran-2-yl)boronic acid This article mentions the following:

While islet amyloid deposition comprising amylin is one of pathol. hallmarks of type 2 diabetes mellitus (T2DM), no useful amylin-imaging probe has been reported. In this study, we evaluated two 99mTc-labeled pyridyl benzofuran derivatives as novel amylin-imaging probes using the newly established islet amyloid model mouse. Binding experiments in vitro demonstrated that [99mTc]1 displayed a higher affinity for amylin aggregates than [99mTc]2. Autoradiog. studies using human pancreas sections with T2DM revealed that [99mTc]1 clearly labeled islet amyloid in T2DM pancreatic sections, while [99mTc]2 did not. Although the initial uptake of [99mTc]1 by the normal mouse pancreas was low (0.74%ID/g at 2 min post-injection), [99mTc]1 showed higher retention in the model mouse pancreas than that of the normal mouse, and exhibited strong binding to amylin aggregates in the living pancreas of the model mice. These results suggest that [99mTc]1 is a potential imaging probe targeting islet amyloids in the T2DM pancreas. In the experiment, the researchers used many compounds, for example, (5-Methoxybenzofuran-2-yl)boronic acid (cas: 551001-79-7Recommanded Product: (5-Methoxybenzofuran-2-yl)boronic acid).

(5-Methoxybenzofuran-2-yl)boronic acid (cas: 551001-79-7) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Recommanded Product: (5-Methoxybenzofuran-2-yl)boronic acid

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem