Two New Limonoids from the Root Bark of Chinese Medicinal Plant Dictamnus dasycarpus was written by Wang, Li-Li;Jiang, Cheng-Shi;Fu, Yan;Chen, Fei-Fei;Lan, Le-Fu;Zhang, Hai-Yan;Guo, Yue-Wei. And the article was included in Helvetica Chimica Acta in 2014.Recommanded Product: 28808-62-0 This article mentions the following:
Two new limonoids, kihadanin C (I) and 23-methoxydasylactone A (II), together with seven related known ones, were isolated from the root bark of the plant Dictamnus dasycarpus. The structures of the new compounds were elucidated on the basis of extensive analyses of their spectroscopic data (1D- and 2D-NMR, MS) and by comparison of their NMR data with those reported in the literature. To the best of our knowledge, I presents the first example of A,D-seco limonoid with an unusual 3,4-dihydroxy-2,5-dimethoxytetrahydrofuran moiety as ring E. In the bioassay in vitro, dasylactone B7 showed moderate antibacterial activity against Staphylococcus aureus, while fraxinellone and isofraxinellone displayed neuroprotective activities against H2O2-induced injury in SH-SY5Y cells. In the experiment, the researchers used many compounds, for example, (3R,3aR)-3-(Furan-3-yl)-3a,7-dimethyl-3a,4,5,6-tetrahydroisobenzofuran-1(3H)-one (cas: 28808-62-0Recommanded Product: 28808-62-0).
(3R,3aR)-3-(Furan-3-yl)-3a,7-dimethyl-3a,4,5,6-tetrahydroisobenzofuran-1(3H)-one (cas: 28808-62-0) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.Recommanded Product: 28808-62-0
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem