Usui, Shinya published the artcileDirect ortho Cupration: A New Route to Regioselectively Functionalized Aromatics, COA of Formula: C8H5IO, the publication is Journal of the American Chemical Society (2007), 129(49), 15102-15103, database is CAplus and MEDLINE.
The authors have developed a direct regio- and chemoselective method for generating functionalized aromatic cuprate compounds through deprotonative directed ortho cupration using TMP(tetramethylpiperidino)-cuprates (R(TMP)Cu(CN)Li2; R = alkyl, Ph, or TMP) that were prepared by mixing of CuCN, RLi, and Li tetramethylpiperidide (LTMP) in THF. Deprotonative cupration of various functionalized benzenes with TMP-cuprate proved effective for the direct generation of o-functionalized Cu aromatic and heteroaromatic derivatives, particularly those with electrophilic functional groups, such as cyano, amide, and halogens. Direct cupration, followed by electrophilic trapping, provided a convenient preparative method for 1,2- or 1,2,3-multisubstituted aromatic compounds, e.g. 95 % 2-iodo-1,3-dimethoxybenzene from 1,3-dimethoxybenzene. The functionalized aromatic cuprate intermediates also undergo oxidation reactions very efficiently and with high regio- and chemoselectivity to afford functionalized phenol, ligand(hetero)-coupling, or homocoupling products by appropriately changing the oxidants and cuprates. The crystal and mol. structures of (TMP)2Cu(CN)Li2THF were determined by x-ray crystallog.
Journal of the American Chemical Society published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C15H24O2, COA of Formula: C8H5IO.
Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem