Top Picks: new discover of 5-Hydroxyisobenzofuran-1,3-dione

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Reference of 27550-59-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.27550-59-0, Name is 5-Hydroxyisobenzofuran-1,3-dione, molecular formula is C8H4O4. In a Article,once mentioned of 27550-59-0

A variety of omega-substituted alkanoic acid (2-amino-phenyl)-amides were designed and synthesized. These compounds were shown to inhibit recombinant human histone deacetylases (HDACs) with IC50 values in the low micromolar range and induce hyperacetylation of histones in whole cells. They induced expression of p21WAF1/Cip1 and caused cell-cycle arrest in human cancer cells. Compounds in this class showed efficacy in human tumor xenograft models.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H2157O – PubChem