Synthesis and biological activities of some new benzofuranopyrazoles was written by Tirlapur, Vijay Kumar;Prasad, Y. Rajendra;Basawaraj, Raga. And the article was included in Indian Journal of Heterocyclic Chemistry in 2010.Electric Literature of C10H7BrO2 This article mentions the following:
1-(5-Bromo-1-benzofur-2-yl)ethanone hydrazone upon treatment with Vilsmeier-Haack reagent underwent cyclization to give 3-(5-bromo-1-benzofur-2-yl)-1H-pyrazole-4-carbaldehyde (I), which further on treatment with acetophenones afforded the corresponding 1-aryl-3-[3-(5-bromo-1-benzofur-2-yl)-1H-pyrazol-4-yl]prop-2-en-1-ones. The reaction of I with aromatic amines in MeOH and also with aromatic amines in the presence of CH2O in dioxan (Mannich reaction) furnished pyrazoles. All newly synthesized compounds were characterized by IR, 1H NMR, and mass spectra and were screened for analgesic, antibacterial, and antifungal activity. Some of the compounds showed good activity when compared with standard drugs. In the experiment, the researchers used many compounds, for example, 1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6Electric Literature of C10H7BrO2).
1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Electric Literature of C10H7BrO2
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem