Thomas Pannakal, Steve published the artcileComprehensive characterization of naturally occurring antioxidants from the twigs of mulberry (Morus alba) using on-line high-performance liquid chromatography coupled with chemical detection and high-resolution mass spectrometry, Recommanded Product: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, the publication is Phytochemical Analysis (2022), 33(1), 105-114, database is CAplus and MEDLINE.
The mulberry tree (Morus alba L.) is a prolific source of biol. active compounds There is considerable growing interest in probing M. alba twigs as a source of disruptive antioxidant lead candidates for cosmetic skin care product development. An integrated approach using high-performance liquid chromatog. (HPLC) coupled with either chem. detection (CD) or high-resolution mass spectrometry (HRMS) was applied to the hydroalcoholic extract of M. alba to detect and identify lead antioxidant compounds, resp. The twigs were weighed, powd. and homogenized using a mill and the extract was prepared using 70% aqueous ethanol. The antioxidant metabolites were detected with HPLC coupled with CD (based on the ORAC assay) and their structural identification was carried out using a Q-Exactive Orbitrap MS instrument. Using this approach, 13 peaks were detected as overall contributors to the antioxidant activity of M. alba , i.e. mulberrosides (A & E), oxyresveratrol & its derivatives, moracin & its derivatives and a dihydroxy-octadecadienoic acid, which together accounted for >90% of the antioxidant activity, highlighting the effectiveness of the integrated approach based on HPLC-CD and HPLC-HRMS. Addnl., a 3,4-dimethoxyphenyl-1-O-β-D-apiofuranosyl-(1 → 6)-O-β-D-glucopyranoside was also discovered for the first time from the twig extract and is presented here. To our knowledge, this is the first report from M. alba twigs using HPLC-CD and HPLC-HRMS that identifies key compounds responsible for the antioxidant property of this native Chinese medicinal plant.
Phytochemical Analysis published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C10H2F12NiO4, Recommanded Product: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol.
Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem