The important role of 5-Bromo-2,3-dihydrobenzofuran

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In an article, published in an article,authors is Bonse, Gerhard, once mentioned the application of 66826-78-6, Name is 5-Bromo-2,3-dihydrobenzofuran,molecular formula is C8H7BrO, is a conventional compound. this article was the specific content is as follows. 66826-78-6

Acylation of Amines with Dichloromaleoyl Chloride

The reaction of dichloromaleoyl chloride (2) with ammonia in ether yields the ammonium salt of (Z)-2,3-dichloro-3-cyanoacrylic acid (6) and with aqueous ammonia the ammonium salt of (Z)-2-amino-3-chloro-3-cyanoacrylic acid (1).With primary aliphatic and aromatic amines dichloromaleamides 8 are obtained, the two chlorine atoms of which can be replaced with other amines to form after cis/trans isomerization diaminofumaramides 11.

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Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H3356O – PubChem