10242-12-3, Name is 5-Nitrobenzofuran-2-carboxylic acid, belongs to benzofuran compound, is a common compound. Quality Control of 5-Nitrobenzofuran-2-carboxylic acidIn an article, once mentioned the new application about 10242-12-3.
A quinolone compound of green high-efficient synthetic method (by machine translation)
The invention discloses a quinolone compound of green high-efficient synthetic method. Method is as follows: step one, the second carbonyl compound, the original carboxylic acid triethyl and the aniline compound three-component raw materials in solvent-free and under the condition of catalyst reaction to obtain the enamine ester intermediate; step b, the enamine ester intermediate re-cyclization reagent ether under the effect of the molecule in the cyclization reaction to obtain the quinolone parent ring compound, the purity of the product up to 98.8% above. The synthesizing method of the invention the main advantages: 1. Step one efficient reaction, without the catalyst solvent use can avoid three waste generating high yield; 2. Step two process green, the cyclization reagent can be reclaimed and reused; 3. The process is simple, steps a and b can be carried out in the same reactor, the reaction end filter to get the quinolone compound. (by machine translation)
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Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H3517O – PubChem