Benzofuran derivatives. I. On the effects of substituents in benzofuran syntheses was written by Suzuki, Tsuneo;Horaguchi, Takaaki;Shimizu, Takahachi;Abe, Teishiro. And the article was included in Bulletin of the Chemical Society of Japan in 1983.Recommanded Product: 1646-27-1 This article mentions the following:
The Rossing (1884) reaction of 4-substituted 2-acylphenoxyacetic acids with NaOAc-Ac2O gives a mixture of benzofurans and 2-benzofurancarboxylic acids. The relative yields of benzofurans and 2-benzofurancarboxylic acids depend on the substituents on the benzene ring of the 2-acylphenoxyacetic acids. Electron-withdrawing substituents such as NO2 favor the formation of 2-benzofurancarboxylic acids. On the other hand, the formation of benzofurans is favored by the steric hindrance of 2-acyl groups in the reaction of 2-acyl-4-nitrophenoxyacetic acids. In the experiment, the researchers used many compounds, for example, Methyl benzofuran-2-carboxylate (cas: 1646-27-1Recommanded Product: 1646-27-1).
Methyl benzofuran-2-carboxylate (cas: 1646-27-1) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.Recommanded Product: 1646-27-1
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem