Some tips on 24673-56-1

24673-56-1 3-Methylbenzofuran-2-carboxylic acid 600591, abenzofuran compound, is more and more widely used in various fields.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.24673-56-1,3-Methylbenzofuran-2-carboxylic acid,as a common compound, the synthetic route is as follows.

Was added to the reaction Schlenk tube equipped with a magnetic stirring bar3-methylbenzofurancarboxylic acid 35.0 mg,Potassium carbonate 55.3 mg,1 mL of dichloromethane and 1 mL of dimethyl sulfoxide.The reaction was carried out by heating at 130 C for 5 hours under air conditions.After the reaction was completed, extraction with ethyl acetate three times, 10 mL each time, the combined organic phases were concentrated.36.6 mg of 2-methylbenzofurancarboxylic acid dichloromethyl ester was obtained.The yield was 71%., 24673-56-1

24673-56-1 3-Methylbenzofuran-2-carboxylic acid 600591, abenzofuran compound, is more and more widely used in various fields.

Reference£º
Patent; Nanchang University; Cai Hu; Fu Zhengjiang; Wang Shuiliang; Jiang Yongqing; Huang Zhicong; (16 pag.)CN109369391; (2019); A;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem