With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.4265-25-2,2-Methylbenzofuran,as a common compound, the synthetic route is as follows.
1.41 g of potassium hydroxide was sequentially added to a 200 mL autoclave.2.82g 2-methylbenzofuran, 30mL absolute ethanol,18 mg of metalloporphyrin tetrakis (o-chlorophenyl)iron porphyrin,Passing 2.0MPa of oxygen,The reaction was carried out at 130 C for 2 hours.The product is acidified, filtered,After recrystallization from hot water, benzofuran-2-carboxylic acid is obtained.The yield was 21.7%.
4265-25-2, 4265-25-2 2-Methylbenzofuran 20263, abenzofuran compound, is more and more widely used in various fields.
Reference£º
Patent; Beijing University of Technology; Bai Jinquan; Li Xinghua; Wang Sinan; Zhang Yahuan; Xie Yabo; Li Jianrong; (5 pag.)CN109206388; (2019); A;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem