127264-14-6, 5-(2-Bromoethyl)-2,3-dihydrobenzofuran is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
The bromo compound 3 (4.54 g, 0.02 mol) and 3-(R)-(1-carbamoyl-1,1-diphenylmethyl)-pyrrolidine (4, 5.6 g, 0.02 mol) were refluxed in acetonitrile containing KOH (1.12 g, 0.02 mol). The reaction mixture was distilled off, water (50 mL) and MDC (50 mL) was added to the obtained residue to form a two-phase mixture. The phases were separated and organic phase was distilled under vacuum. The obtained residue was dissolved in methyl ethyl ketone (10 mL) and filtered to eliminate un-dissolved solid. The 48percent HBr (0.344 g, 0.00204 mol) was added to the filtrate and distilled under vacuum to afford solid foam. The foam was scurried in diisopropylether and filtered to get the title compound in 7 g yield.
127264-14-6, 127264-14-6 5-(2-Bromoethyl)-2,3-dihydrobenzofuran 21831160, abenzofuran compound, is more and more widely used in various fields.
Reference£º
Article; Vasantha; Lakshmanarao; Srinivasa Rao; Sivalakshmi Devi; Venkata Suryanarayana; Indian Journal of Chemistry – Section B Organic and Medicinal Chemistry; vol. 52; 6; (2013); p. 824 – 828;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem