Simple exploration of 77095-51-3

As the paragraph descriping shows that 77095-51-3 is playing an increasingly important role.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.77095-51-3,Benzofuran-6-carboxylic acid,as a common compound, the synthetic route is as follows.,77095-51-3

Benzofuran carboxylic acid (II) (1.0 g, 6.17 mmol, 1.0 equiv), DMF (0.01 eq) and THF (10 mL, 10 vol) is charged to a two-neck round bottom flask under nitrogen atmosphere. Oxalyl chloride (1.1 mL, 13.34 mmol, 2.0 equiv) is slowly added while keeping the temperature between 20 to 30 C. The resulting solution was stirred at 20-30 C. for over 2 hr. When the reaction was complete as determined by TLC analysis, the solvent was removed under reduced pressure and the acid chloride of compound of Formula II (Formula IIb) was stored under nitrogen.

As the paragraph descriping shows that 77095-51-3 is playing an increasingly important role.

Reference£º
Patent; ScinoPharm Taiwan, Ltd.; WU, Ming-Chih; HSIAO, Tsung-Yu; US2019/2445; (2019); A1;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem