Royer, Rene et al. published their research in European Journal of Medicinal Chemistry in 1974 |CAS: 53724-96-2

The Article related to benzofurancarboxylate nitration acetylation, structure activity nitrobenzofuran, amebicide nitro benzofurancarboxylate, trichomonacide nitro benzofurancarboxylate, Heterocyclic Compounds (One Hetero Atom): Areno- and Diarenofurans and other aspects.Safety of Ethyl 6-methoxy-3-methylbenzofuran-2-carboxylate

Royer, Rene; Lamotte, Genevieve; Demerseman, Pierre; Platzer, Nicole; Cavier, Raymond published an article in 1974, the title of the article was Nitro derivatives of biological interest. VIII. Comparative orientations of nitration and acetylation of 3-methyl-4-methoxyl ethyl coumarilates.Safety of Ethyl 6-methoxy-3-methylbenzofuran-2-carboxylate And the article contains the following content:

Nitration of the 4 methoxycoumarilates I occurred mainly in the benzene ring, although in some cases the nitromethyl derivative was also detected. I were also acetylated in the benzene ring and the acetylated or nitrated esters hydrolyzed and decarboxylated, and the decarboxylation products again nitrated. Only the 2-nitro derivatives were amebicides and trichomonacides. The experimental process involved the reaction of Ethyl 6-methoxy-3-methylbenzofuran-2-carboxylate(cas: 53724-96-2).Safety of Ethyl 6-methoxy-3-methylbenzofuran-2-carboxylate

The Article related to benzofurancarboxylate nitration acetylation, structure activity nitrobenzofuran, amebicide nitro benzofurancarboxylate, trichomonacide nitro benzofurancarboxylate, Heterocyclic Compounds (One Hetero Atom): Areno- and Diarenofurans and other aspects.Safety of Ethyl 6-methoxy-3-methylbenzofuran-2-carboxylate

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem