Royer, Mariana’s team published research in International Biodeterioration & Biodegradation in 70 | CAS: 56317-21-6

International Biodeterioration & Biodegradation published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Product Details of C14H10O4.

Royer, Mariana published the artcileEfficacy of Bagassa guianensis Aubl. extract against wood decay and human pathogenic fungi, Product Details of C14H10O4, the publication is International Biodeterioration & Biodegradation (2012), 55-59, database is CAplus.

Extractives that provide natural resistance to Bagassa guianensis Aubl. heartwood were examined Soil-bed tests showed that the B. guianensis heartwood resistance was significantly reduced after Et acetate extraction, whereas methanol and especially water extractions improved the resistance. The Et acetate extract was submitted to a bioguided fractionation, and fractions were tested against one wood-destroying fungal strain (Pycnoporus sanguineus) and two human pathogenic fungal strains (Candida glabrata (yeast) and Trichophyton rubrum (filamentous dermatophyte)). Fraction F7, which exhibited the strongest antifungal activity, was subsequently fractionated by high performance liquid chromatog. (HPLC). Six previously described compounds were isolated. Although the two moracins, 6-O-methyl-moracin N (3) and moracin N (4) were the most active against fungal strains with MIC values between 4 and 16 μg ml-1, the isolated compounds showed less or equivalent antifungal activity than the initial fraction. Possible synergism between compounds 3 and 4 and other secondary metabolites have been hypothesized. Our study demonstrated that this extract as a whole might be used as a wood preservation or antimycotic product.

International Biodeterioration & Biodegradation published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Product Details of C14H10O4.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem