Rehan, Mohammad published the artcileSynthesis of Functionalized Benzo[b]furans via Oxidative Cyclization of o-Cinnamyl Phenols, Synthetic Route of 13391-27-0, the main research area is cinnamyl phenol palladium oxidative cyclization catalyst; benzofuran benzyl preparation.
Disclosed herein is an efficient synthetic route for the synthesis of functionalized 2-benzyl benzo[b]furans I (R1 = 5-Me, 5-OMe, 5-Ph, 4,6-diMe, etc.; R2 = Ph, 4-MeC6H4, 4-FC6H4, 4-ClC6H4, H, Me, etc.; Ar = Ph, 4-MeC6H4, 4-FC6H4, 4-ClC6H4, 1-naphthyl, etc.) via a regioselective 5-exo-trig intramol. oxidative cyclization of ortho-cinnamyl phenols using [PdCl2(CH3CN)2] as catalyst and benzoquinone as an oxidant. Further, a sequential ortho-cinnamylation of phenols using cinnamyl alcs. catalyzed by Re2O7, followed by an oxidative cyclization using the above Pd catalyst, is performed. The reaction showed broad substrate scope with good to excellent yields.
Journal of Organic Chemistry published new progress about Alkenylation, cinnamylation. 13391-27-0 belongs to class benzofurans, name is 5-Methoxy-2-methylbenzofuran, and the molecular formula is C10H10O2, Synthetic Route of 13391-27-0.
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem