《Carbon quantum dots embedded electrospun nanofibers for efficient antibacterial photodynamic inactivation》 was written by Nie, Xiaolin; Wu, Shuanglin; Mensah, Alfred; Lu, Keyu; Wei, Qufu. Synthetic Route of C20H14O And the article was included in Materials Science & Engineering, C: Materials for Biological Applications in 2020. The article conveys some information:
Faced with the emergence and proliferation of antibiotic resistant pathogens, novel nonspecific materials and approaches are required. Herein, we employed electrospinning technol. to fabricate nanofibers with antibacterial photodynamic inactivation. This material combines polyacrylonitrile, as a photostable polymer, and biocompatible carbon quantum dots. The resulted nanofibers were successfully characterized by phys. and spectroscopic methods. The microbicidal reactive oxygen species (i.e., singlet oxygen) upon illumination was confirmed, and cytotoxicity assay demonstrated that the nanofibers had low cytotoxicity and good biocompatibility. Antibacterial photodynamic inactivation studies demonstrated broad antibacterial efficacy of Gram-neg. Escherichia coli ATCC-8099 (99.9999+%, 6 log units inactivation), Gram-neg. Pseudomonas aeruginosa CMCC (B) 10104 (99.9999+%, 6 log units inactivation), and Gram-pos. Bacillus subtilis CMCC (B) 63501 (99.9999+%, 6 log units inactivation) upon illumination with visible light (Xe lamp, 500 W, 12 cm sample distance). However modest inactivation results were observed against Gram-pos. Staphylococcus aureus ATCC-6538 (98.3%, 1.8 log units inactivation). Owing to the prepared nanofibers exhibiting efficient antibacterial activity against Gram-neg. and Gram-pos. bacteria, such materials could be potentially used in anti-infective therapy. After reading the article, we found that the author used 1,3-Diphenylisobenzofuran(cas: 5471-63-6Synthetic Route of C20H14O)
1,3-Diphenylisobenzofuran(cas: 5471-63-6) can be used as a fluorescent probe for detection of superoxide anion radical (O2−) inside the membrane lipid layer by DPBF fluorescence quenching method. 1,3-Diphenylisobenzofuran(DPBF) can be used to study the single crystal molecular structure and solution photophysical properties of DPBF.Synthetic Route of C20H14O
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem