New learning discoveries about 42933-43-7

42933-43-7, 42933-43-7 2,3-Dihydrobenzofuran-5-amine 3841102, abenzofuran compound, is more and more widely used in various fields.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.42933-43-7,2,3-Dihydrobenzofuran-5-amine,as a common compound, the synthetic route is as follows.

Ac2O (2 equiv) and pyridine (1 equiv) were added dropwise to a stirred solution of compound 7 or 8, respectively, (1 equiv) in dioxane (4 mL) at 0C and the solution was stirred at 20C for 16 h. The solution was diluted with water (50 mL) and extracted with ethyl acetate (350 mL). The organic layer was washed with brine, dried over MgSO4, and then evaporated to give 9 (99%) as a brown solid or 10 (86%) as a white solid

42933-43-7, 42933-43-7 2,3-Dihydrobenzofuran-5-amine 3841102, abenzofuran compound, is more and more widely used in various fields.

Reference£º
Article; Lee, Jeewoo; Tran, Phuong-Thao; Hoang, Van-Hai; Thorat, Shivaji A.; Kim, Sung Eun; Ann, Jihyae; Chang, Yu Jin; Nam, Dong Woo; Song, Hyundong; Mook-Jung, Inhee; Lee, Jiyoun; Bioorganic and Medicinal Chemistry; vol. 21; 13; (2013); p. 3821 – 3830;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem