35700-40-4, 2,3-Dihydrobenzofuran-7-carboxylic acid is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A suspension of 2,3-dihydro-benzofiran-7-carboxylic acid, (TCI, 20.0 g, 121.8 mmol) in 600 mL of dry acetonitrile was cooled to 0 0C and treated with N,O-dirnethylhydroxylamine hydrochloride (14.25 g, 146.1 mmol). The reaction was allowed to stirfor 10 minutes and EDCI (24.6 g, 158.3 mmol) was added, followed by HOBT (3.2 g, 24.2 mmol) and the resulting mixture was allowed to stirfor 5 minutes. Triethylamine (365.4 mmol) was then added and the reaction mixture was allowed to stirfor 18 hours at room temperature, then diluted with aqueous IN HCl (250 mL) and extracted with ethyl acetate (1.0 L). The organic layer was sequentially washed with aqueous 10% potassium carbonate (200 mL), aqueous IN HCl (200 mL), and brine (200 mL). The organic layer was then dried over magnesium sulfate, filtered and concentrated in vacuo to provide compound 2A (23.37 g, 93 %) as a colorless oil. M.S. found for CnHnNO3: 230.1 1 (M^Na)+.
35700-40-4 2,3-Dihydrobenzofuran-7-carboxylic acid 2795014, abenzofuran compound, is more and more widely used in various.
Reference£º
Patent; SCHERING CORPORATION; WO2009/152200; (2009); A1;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem