One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, HPLC of Formula: C15H10FNO, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 64169-67-1, Name is 1-(4-Fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile, molecular formula is C15H10FNO
alpha-Fluorination of carbonyls with nucleophilic fluorine
Given the unique properties of fluorine, and the ability of fluorination to change the properties of organic molecules, there is significant interest from medicinal chemists in innovative methodologies that enable the synthesis of new fluorinated motifs. State-of-the-art syntheses of alpha-fluorinated carbonyl compounds invariably rely on electrophilic fluorinating agents, which can be strongly oxidizing and difficult to handle. Here we show that reversing the polarity of the enolate partner to that of an enolonium enables nucleophilic fluorinating agents to be used for direct chemoselective alpha-C?H-fluorination of amides. Reduction of these products enables facile access to beta-fluorinated amines and the value of this methodology is shown by the easy preparation of a number of fluorinated analogues of drugs and agrochemicals. A fluorinated analogue of citalopram, a marketed antidepressant drug, is presented as an example of the preserved biological activity after fluorination.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, HPLC of Formula: C15H10FNO, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 64169-67-1
Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H3893O – PubChem