One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 174775-48-5, Name is Ethyl 5-aminobenzofuran-2-carboxylate, formurla is C11H11NO3. In a document, author is Rao, Min, introducing its new discovery. Computed Properties of C11H11NO3.
Copper-Catalyzed C-H Difluoroalkylation of Coumarins with Fluoroalkyl Bromides
An efficient method for the copper-catalyzed selective C-H difluoroalkylation of coumarins and with low cost and readily available ethyl bromodifluoroacetate andN-phenyl bromodifluoroacetamide has been reported. This reaction exhibits good functional group tolerance with respect to coumarins and difluoroalkylation reagents, and several redox-sensitive substrates have been successfully C-H difluoroalkylated in good to high yield. This design could further expand the scope to other heteroarenes, including furan, benzofuran, pyrrole, pyridinone, chromenone, indole, and quinolinone. A mechanism involving copper-catalyzed in-situ generation of fluoroalkyl radical is proposed.
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Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem