Aromatic spirans. XXI. Syntheses of methyl substituted phthalaldehydic acids and their ethyl and methyl esters as synthones for syntheses of methylated 2,2′-spirobiindandiones was written by Neudeck, H. K.. And the article was included in Monatshefte fuer Chemie in 1996.Synthetic Route of C9H8O2 This article mentions the following:
The preparation of 3-hydroxy(methyl)-1(3H)-isobenzofuranones I (i.e., phthalaldehydic acids) was described. I are intermediates for methylated 2,2′-spirobiindandiones (no data). In the experiment, the researchers used many compounds, for example, 5-Methylisobenzofuran-1(3H)-one (cas: 54120-64-8Synthetic Route of C9H8O2).
5-Methylisobenzofuran-1(3H)-one (cas: 54120-64-8) belongs to benzofurans derivatives. Benzofuran derivatives have shown many biological activities, including antifungal and antimicrobial properties, and acting as antagonists of H3 receptors and angiotensin II. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Synthetic Route of C9H8O2
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem