Identification of potentially toxic compounds in complex extracts of environmental samples using gas chromatography-mass spectrometry and multivariate data analysis was written by Bergknut, Magnus;Kucera, Adam;Frech, Kristina;Andersson, Erika;Engwall, Magnus;Rannug, Ulf;Koci, Vladimir;Andersson, Patrik L.;Haglund, Peter;Tysklind, Mats. And the article was included in Environmental Toxicology and Chemistry in 2007.Computed Properties of C16H10O This article mentions the following:
In this study, the authors examined 31 samples of varying chem. composition, including samples of soils from gasworks, coke production sites, and sites where wood preservatives were heavily used; ash and soot from municipal solid waste incinerators; antiskid sand; and dust from areas with heavy road traffic. The samples were comprehensively chem. characterized, especially their polycyclic aromatic compound contents, using gas chromatog.-time-of-flight mass spectrometry, whereas their biol. effects were assessed using dehydrogenase activity, root growth (Hordeum vulgare), reproduction of springtails (Folsomia candida), algal growth (Desmodesmus subspicatus), germinability (Sinapis alba), Vibrio fischeri, DR-CALUX, and Ames Salmonella assays. The number of compounds detected in the samples ranged from 123 to 527. Using the multivariate regression technique of partial-least-squares projections to latent structures, it was possible to find individual compounds that exhibited strong correlations with the different biol. responses. Some of the results, however, indicate that a broader chem. characterization may be needed to identify all the compounds that may cause the measured biol. responses. In the experiment, the researchers used many compounds, for example, Naphtho[2,1-b]benzofuran (cas: 205-39-0Computed Properties of C16H10O).
Naphtho[2,1-b]benzofuran (cas: 205-39-0) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.Computed Properties of C16H10O
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem