The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: (R)-Ethyl 4-chloro-3-hydroxybutanoate(SMILESS: O=C(OCC)C[C@@H](O)CCl,cas:90866-33-4) is researched.Computed Properties of CAgF3O3S. The article 《Synthesis of ethyl (R)-4-chloro-3-hydroxybutanoate with recombinant Escherichia coli cells expressing (S)-specific secondary alcohol dehydrogenase》 in relation to this compound, is published in Bioscience, Biotechnology, and Biochemistry. Let’s take a look at the latest research on this compound (cas:90866-33-4).
The synthesis of Et (R)-4-chloro-3-hydroxybutanoate ((R)-ECHB) from Et 4-chloroacetoacetate was studied using whole recombinant cells of Escherichia coli expressing a secondary alc. dehydrogenase of Candida parasilosis. Using 2-propanol as an energy source to regenerate NADH, the yield of (R)-ECHB reached 36.6 g/l (more than 99% ee, 95.2% conversion yield) without addition of NADH to the reaction mixture
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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem