Ilagouma, A. T. published the artcileArylcyclohexylamines derived from BTCP are potent indirect catecholamine agonists, Category: benzofurans, the publication is European Journal of Medicinal Chemistry (1993), 28(5), 377-85, database is CAplus.
N-[1-(2-Benzo[b]thiophenyl)cyclohexyl]piperidine (BTCP)-related mols., e.g. I (R1 = 2-benzo[b]thiophenyl, 2-benzo[b]furanyl, 2-naphthyl, 1-naphthyl, R2 = H, 3-Me, 3,5-Me2, 4-Me, 3-HOCH2, 3-AcOCH2, 4-BrCH2, 3-ICH2, 3-ClCH2, R3 = H, 2-Me, 3-Me, 4-Me, 4-CMe3) were prepared by chem. modulation of the 3 rings which constitute this dopamine (DA) and norepinephrine (NE) uptake inhibitor. The prepared compounds showed good homogeneity of action when tested in vitro [binding to the DA uptake complex and to the phencyclidine (PCP) receptor sites, inhibition of the synaptosomal uptake of DA and NE] and in vivo (locomotor activity in mice). The newly prepared structures, although formally related to the PCP structural model, no longer display significant affinity for the PCP receptor. These compounds behave like a new series of indirect potent stimulants of the dopaminergic and noradrenergic systems leading to potential antidepressive compounds
European Journal of Medicinal Chemistry published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Category: benzofurans.
Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem