SDS of cas: 87-41-2. Recently I am researching about THIOUREA DERIVATIVES; ANTIFUNGAL ACTIVITY; CRYSTAL; ACID; TRIFLUOROMETHYLATION; ANTIMALARIAL; DISCOVERY; HIV, Saw an article supported by the UEFISCDIConsiliul National al Cercetarii Stiintifice (CNCS)Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii (UEFISCDI) [PN-III-P4-ID-PCCF-2016-0114, 52 PCCDI]. Published in MDPI in BASEL ,Authors: Limban, C; Chifiriuc, MC; Caproiu, MT; Dumitrascu, F; Ferbinteanu, M; Pintilie, L; Stefaniu, A; Vlad, IM; Bleotu, C; Marutescu, LG; Nuta, DC. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one
The increasing threat of antimicrobial resistance to all currently available therapeutic agents has urged the development of novel antimicrobials. In this context, a series of new benzoylthiourea derivatives substituted with one or more fluorine atoms and with the trifluoromethyl group have been tested, synthesized, and characterized by IR, NMR, CHNS and crystal X-ray diffraction. The molecular docking has provided information regarding the binding affinity and the orientation of the new compounds to Escherichia coli DNA gyrase B. The docking score predicted the antimicrobial activity of the studied compounds, especially against E. coli, which was further demonstrated experimentally against planktonic and biofilm embedded bacterial and fungal cells. The compounds bearing one fluorine atom on the phenyl ring have shown the best antibacterial effect, while those with three fluorine atoms exhibited the most intensive antifungal activity. All tested compounds exhibited antibiofilm activity, correlated with the trifluoromethyl substituent, most favorable in para position.
SDS of cas: 87-41-2. Bye, fridends, I hope you can learn more about C8H6O2, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem