Hirota, Takashi; Fujita, Hiroko; Sasaki, Kenji; Namba, Tetsuto published their research in Journal of Heterocyclic Chemistry on December 31 ,1986. The article was titled 《A novel synthesis of benzofuran and related compounds. III. The Vilsmeier reaction of phenoxyacetaldehyde diethyl acetals》.Application of 53860-74-5 The article contains the following contents:
2-Benzofurancarboxaldehydes, e.g., I (R = H, OMe; R1 = OMe, OEt, NEt2) were prepared in 15-58% yields by the Vilsmeier reaction 3,5-RR1C6H3OCH2CH(OEt)2 (II). A rare geminidiol III was isolated in one case. II were prepared in 65-91% yields by treating 3,5-RR1C6H3ONa with BrCH2CH(OEt)2. In the experiment, the researchers used 6-Methoxybenzofuran-2-carbaldehyde(cas: 53860-74-5Application of 53860-74-5)
6-Methoxybenzofuran-2-carbaldehyde(cas: 53860-74-5) belongs to benzofurans.Application of 53860-74-5Benzofurans containing one furan ring that have been implicated as psychoactive recreational drugs include 6-(2-aminopropyl)benzofuran (6-APB), 5-(2-aminopropyl)benzofuran (5-APB), 5-(2-ethylaminopropyl)benzofuran (5-EAPB), and 5-methylaminopropylbenzofuran (5-MAPB).
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem