Synthetic Route of 13099-95-1, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 13099-95-1, Name is Ethyl 3-oxo-2,3-dihydrobenzofuran-2-carboxylate,introducing its new discovery.
In the present study we have made an attempt to synthesize novel benzofuran derivatives and evaluate them for anticancer screening. First, 2-carbethoxy-3 (2H) benzofuranone (2) was prepared by the condensation of ethyl bromomalonate with methyl salicylate (1) in presence of anhydrous potassium carbonate. Treatment of 2- carbethoxy-3 (2H) benzofuranone (2) with dimethylsulphate in presence of anhydrous potassium carbonate afforded 2-carbethoxy-3-methoxy benzofuranone (3). 2- Carbethoxy-3-methoxy benzofuranone (3) on treatment with hydrazine hydrate gave 3-methoxybenzofuran-2-carbohydrazide (4) and then condensation of 3- methoxybenzofuran-2-carbohydrazide (4) with various substituted benzaldehydes led to a novel series of benzofuran derivatives (5a-k). The synthesized compounds were analyzed by physical and analytical data. The synthesized compounds were evaluated for their short-term anticancer activity. The synthesized benzofuran derivative possessed significant cytotoxic activity against Ehrlich’s Ascites Carcinoma (EAC) cell lines and HEP2 cell line by Sulforhodamine B assay.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 13099-95-1, and how the biochemistry of the body works.Synthetic Route of 13099-95-1
Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3503O – PubChem