Category: benzofurans. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: (R)-Ethyl 4-chloro-3-hydroxybutanoate, is researched, Molecular C6H11ClO3, CAS is 90866-33-4, about Synthesis of 4-Hydroxy-2-oxo-1-pyrrolidineacetamide. Author is Chen, Xue; Lei, Yingjie; Ding, Mei; Bi, Ye.
Asym. reduction of Et 4-chloro-3-oxobutanoate to the title compound (i.e. (R)-oxyracetam) catalyzed by Saccharomyces cerevisiae and followed with the condensation of 2-amino-acetamide in alk. solution was investigated. The target compound was obtained in 52.7% yield and confirmed by sp. rotation and 1H NMR.
After consulting a lot of data, we found that this compound(90866-33-4)Category: benzofurans can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem