143878-29-9, Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
25 g of intermediate (IV) was added to 140 mL of water and 27 mL of propylene glycol monomethyl ether, stirred,Add 20mL 50% sodium hydroxide solution, the system temperature to 90-100 , stirring temperature 12h,Stirring speed 300r / min, cooling to 0-10 , stirring 1h, filtered to obtain solid (intermediate sodium salt).The sodium salt of intermediate V was added to 200 mL of water and 40 mL of propylene glycol monomethyl ether and the temperature was raised to 75-85 C,Dropping 10mL concentrated hydrochloric acid, pH 1-2, precipitation of solid, cooling to 0-10 , stirring 1h,Stirring speed 300r / min, suction filtration, washing, drying at 50-60 for 8h to obtain intermediates (V)White solid, 13.2 g, yield 66%, purity 100.0% (HPLC)., 143878-29-9
143878-29-9 Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate 10635698, abenzofuran compound, is more and more widely used in various fields.
Reference£º
Patent; Fuxin Fengcheng Chemical Technology Development Co., Ltd; Wang, Ji; Cao, Ronghao; (7 pag.)CN106316998; (2017); A;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem