Microwave-promoted Heck and Suzuki coupling reactions of new 3-(5-bromobenzofuranyl)pyrazole in aqueous media was written by Dawood, Kamal M.;Darweesh, Ahmed F.;Shaaban, Mohamed R.;Farag, Ahmad M.. And the article was included in ARKIVOC (Gainesville, FL, United States) in 2018.Computed Properties of C10H7BrO2 This article mentions the following:
Suzuki-Miyaura and Mizoroki-Heck cross-coupling reactions of 3-(5-bromobenzofuran-2-yl)-1H-pyrazole with arylboronic acids and terminal olefins resp. were investigated using a benzothiazole-oxime palladium(II) complex, under both thermal and microwave-irradiation conditions in an open vessel using aqueous solvent. The benzothiazole-oxime-based Pd(II) complex was found to be an efficient and highly active pre-catalyst for the cross-coupling reactions, and for the preparation of new C-C cross-coupled compounds such as biaryls I [Ar = Ph, 4-MeC6H4, 3-thienyl, etc.] and alkenes II [R = CN, CO2Et, CO2Bu, Ph] of potential biol. interest which were difficult to obtain using other synthetic routes. In the experiment, the researchers used many compounds, for example, 1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6Computed Properties of C10H7BrO2).
1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antiviral, antimicrobial, antitumor, anti-inflammatory.Computed Properties of C10H7BrO2
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem