Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. name: 5-Chloroisobenzofuran-1(3H)-one. Introducing a new discovery about 54109-03-4, Name is 5-Chloroisobenzofuran-1(3H)-one
Salen-Cu(II) complex catalysed N-arylation of pyrazole under mild conditions
Three inexpensive and air-/moisture-stable complexes (Salden)Cu (Salden = N, N’-bis(salicylidene)-1,2-dimethylethylenediamine), (Saldch)Cu (Saldch = N, N’-bis(salicylidene)-1,2-cyclohexenediamine), and (Salph)Cu (salph = N, N’-bis(salicylidene)-1,2-phenylenediamine) were synthesised and evaluated as catalysts for the N-arylation of pyrazole with aryl halides. A variety of aryl iodides and bromides underwent coupling with pyrazole, promoted by the (Saldch)Cu complex, in moderate to excellent yields without the protection by an inert gas.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.name: 5-Chloroisobenzofuran-1(3H)-one, you can also check out more blogs about54109-03-4
Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H2627O – PubChem