Brikci-Nigassa, Nahida Mokhtari published the artcile2-Aminophenones, a common precursor to N-aryl isatins and acridines endowed with bioactivities, Formula: C8H5IO, the publication is Tetrahedron (2018), 74(15), 1785-1801, database is CAplus.
Because N-arylation of isatin only worked with iodoferrocene (and in low yield), N-arylation of 2-aminophenones and subsequent oxidative cyclization was employed to access the various N-arylated isatins. It was observed that N-arylation using 2-iodofuran, 2-iodobenzofuran and 2-iodobenzothiophene did not lead to the expected derivatives, but (benzo)furo- and (benzo)thieno[2,3-b]quinolines were formed. Sep. cyclization was also performed under acidic conditions on 2-(arylamino)phenones in order to obtain acridines and related compounds Most of the synthesized compounds were screened for their antiproliferative activity in A2058 melanoma cells and against a panel of disease-relevant kinases such as mammalian CDK5/p25, PIM1, CLK1, DYRK1A, GSK3α/β, Haspin and leishmanial CK1. The biol. results were reported.
Tetrahedron published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Formula: C8H5IO.
Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem