Synthetic Route of 13099-95-1, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 13099-95-1, Name is Ethyl 3-oxo-2,3-dihydrobenzofuran-2-carboxylate,introducing its new discovery.
Synthesis of some antimicrobial heterocycles from pyranotetrahydrocarbazole
3,8-Dioxo-8,9,10,11-tetrahydropyrano[2,3-c]carbazole on dehydrogenation with 5% Pd-C in diphenyl ether gives 8-hydroxy-3-oxopyrano[2,3-c]carbazole 1 which on Pechmann condensation with various acyclic, cyclic, aromatic and heterocyclic beta-keto esters like ethylacetoacetate, ethyl cyclopentonone-2-carboxylate, ethyl 2,3-dihydro-3-oxobenzofuran-2-carboxylate yield 4-methyl-2,9-dioxodipyrano[2?,3?-a:3,2-g]carbazole 2, 2,10-dioxo2?,3?dihydrocyclopenta[4?,57Prime;:5?, 4?]-dipyrano[2?,3?-a:3,2-g]carbazole 3,2, 12-dioxo[1] benzofuran[2?, 3?:5?, 4?]dipyrano[2?,3?-a:3, 2-g]carbazole 4 respectively. With malonic acid and malononitrile it gave 4-hydroxy-2,9-dioxodipyrano[2?,3?-a:3,2-g] carbazole 5 and 2-amino-3-cyano-2?,9-dioxospiro[dipyrano[2?,3?-a:3,2-g] carbazole-4,3?-indole] 6 respectively. The structures of the compounds have been established on the basis of spectral and analytical data. All the compound 1a-d, 2a-d, 3a-d, 4a-d, 5a-d and 6a-d have been screened for their antimicrobial activity and have been found to exhibit significant antibacterial and antifungal activity.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 13099-95-1, and how the biochemistry of the body works.Synthetic Route of 13099-95-1
Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H3498O – PubChem