42933-43-7, 2,3-Dihydrobenzofuran-5-amine is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
The 2,3-Dihydrobenzofuran-5-amine (1A) (2.0g, 14 . 80mmol) is added to the hydrochloric acid in (14.6 ml, 3N), cooling to -5 ¡ãC, dropping sodium nitrite (1.2g, 17 . 80mmol) of water (8 ml) solution, after dripping, in 0 ¡ãC reaction 30 minutes, slowly adding sodium acetate (2.1g, 25 . 6mmol), adjusting reaction solution pH=5-6, in 0-5 ¡ãC lower, dropping ethyl 2-chloroacetoacetate(2.4g, 14 . 80mmol) methanol (5 ml) solution, to reaction at room temperature 2 hours. Adding ethyl acetate to the reaction solution (20 ml), liquid, organic phase with saturated salt water (30 ml) washing, dry anhydrous sodium sulfate, filtered, concentrated under reduced pressure, the residue is purified by silica gel column chromatography (ethyl acetate/petroleum ether (v/v) =1:99-1:9) to obtain the title compound ethyl 2-chloro-2-(2-(2,3-dihydrobenzofuran-5-yl)hydrazono)acetate(1B), yellow solid (200 mg, yield 5percent).
42933-43-7, As the paragraph descriping shows that 42933-43-7 is playing an increasingly important role.
Reference£º
Patent; SICHUAN HAISCO PHARMACEUTICAL CO LTD; WEI, YONGGANG; QIU, GUANPENG; LEI, BAILIN; LU, YONGHUA; (120 pag.)CN104395312; (2016); B;,
Benzofuran – Wikipedia
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