Brief introduction of 23145-07-5

The synthetic route of 23145-07-5 has been constantly updated, and we look forward to future research findings.

23145-07-5, 5-Bromobenzofuran is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Compound 4 (5-bromobenzofuran, 5.4 g, 27.5 mmol),Compound 13 (4,4,5,5-tetramethyl-2-(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)-1,3,2-dioxaborolan , 7.6g, 25.0mmol) dissolved in MeOH(8.0 mL, 1 mL/g), toluene (80.0 mL, 10 mL/g),Further, Cs2CO3 (16.3 g, 50.0 mmol) was added, followed by nitrogen.Pd(PPh3)4 (1.4 g, 1.2 mmol) was added under nitrogen.It was then stirred under reflux for 3 hours. After the reaction,The reaction was filtered through celite and concentrated under reduced pressure.Silica gel column chromatography (hexane: EtOAc = 5:1)Purification was carried out to give a white solid compound 14 (5.3 g, yield 72percent).

The synthetic route of 23145-07-5 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Dongjin Shimeiken Co., Ltd.; Cui Zhenyu; Jiang Bingnan; Yin Xingyi; Song Zhenyin; Jin Xingxie; Li Dongxuan; Cui Zhien; Li Xuanzhi; Shen Guichun; (45 pag.)CN109206387; (2019); A;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem