In an article, author is Zhou, Rong, once mentioned the application of 14400-67-0, Category: benzofurans, Name is 2,5-Dimethylfuran-3(2H)-one, molecular formula is C6H8O2, molecular weight is 112.13, MDL number is MFCD00052571, category is benzofurans. Now introduce a scientific discovery about this category.
Selenium-Catalyzed Carbonylative Synthesis of 3,4-Dihydroquinazolin-2(1H)-one Derivatives with TFBen as the CO Source
An efficient and general carbonylative procedure for the synthesis of 3,4-dihydroquinazolin-2(1H)-one from 1-(halomethyl)-2-nitrobenzenes and aryl/alkyl amines have been explored. In this approach, to avoid of using toxic CO gas, a solid and stable CO precursor, TFBen (benzene-1,3,5-triyl triformate), was utilized. With elemental selenium as the catalyst, a variety of aryl/alkyl amines has been tolerated well to afford the corresponding 3,4-dihydroquinazolin-2(1H)-one products in moderate to excellent yields under mild reaction condition.
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Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem