Awesome Chemistry Experiments For 6-Fluoroisobenzofuran-1(3H)-one

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Formula: C8H5FO2, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 23932-84-5, in my other articles.

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Formula: C8H5FO2, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 23932-84-5, Name is 6-Fluoroisobenzofuran-1(3H)-one, molecular formula is C8H5FO2

3-Nitroindenoisoquinoline human topoisomerase IB (Top1) poisons have potent antiproliferative effects on cancer cells. The undesirable nitro toxicophore could hypothetically be replaced by other functional groups that would retain the desired biological activities and minimize potential safety risks. Eleven series of indenoisoquinolines bearing 3-nitro bioisosteres were synthesized. The molecules were evaluated in the Top1-mediated DNA cleavage assay and in the National Cancer Institute’s 60 cell line cytotoxicity assay. The data reveal that fluorine and chlorine may substitute for the 3-nitro group with minimal loss of Top1 poisoning activity. The new information gained from these efforts can be used to design novel indenoisoquinolines with improved safety.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Formula: C8H5FO2, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 23932-84-5, in my other articles.

Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H1525O – PubChem