So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Imamura, Yorishige; Shigemori, Keiko; Ichibagase, Hisashi researched the compound: Sodium 4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-ide( cas:129-18-0 ).Recommanded Product: Sodium 4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-ide.They published the article 《Effects of simultaneous administration of drugs on absorption and excretion. V. Effect of phenylbutazone on antibacterial activity and distribution of sulfadimethoxine in rabbits》 about this compound( cas:129-18-0 ) in Chemical & Pharmaceutical Bulletin. Keywords: sulfadimethoxine bactericide pharmacokinetics phenylbutazone; sulfanilamide pharmacokinetics phenylbutazone; salicylate sulfanilamide pharmacokinetics. We’ll tell you more about this compound (cas:129-18-0).
The antibacterial activities of sulfadimethoxine [122-11-2] (25 mg/kg, i.v.) in rabbit plasma were significantly increased by concomitant injection of Na phenylbutazone (Na I) [129-18-0] (50 mg/kg, i.v.). The levels of unchanged sulfadimethoxine in rabbit plasma were significantly reduced by concomitant injection of phenylbutazone. These results suggest that phenylbutazone increases the transfer of sulfadimethoxine from plasma to tissues in rabbits.
There is still a lot of research devoted to this compound(SMILES：O=C(N(C1=CC=CC=C1)N2C3=CC=CC=C3)[C-](CCCC)C2=O.[Na+])Recommanded Product: Sodium 4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-ide, and with the development of science, more effects of this compound(129-18-0) can be discovered.
Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem