Del Poeta, Maurizio et al. published their research in Antimicrobial Agents and Chemotherapy in 1998 | CAS: 38220-75-6

1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Recommanded Product: 1-(5-Bromobenzofuran-2-yl)ethanone

Structure-in vitro activity relationships of pentamidine analogs and dication-substituted bis-benzimidazoles as new antifungal agents was written by Del Poeta, Maurizio;Schell, Wiley A.;Dykstra, Christine C.;Jones, Susan;Tidwell, Richard R.;Czarny, Agnieszka;Bajic, Miroslav;Bajic, Marina;Kumar, Arvind;Boykin, David;Perfect, John R.. And the article was included in Antimicrobial Agents and Chemotherapy in 1998.Recommanded Product: 1-(5-Bromobenzofuran-2-yl)ethanone This article mentions the following:

Twenty analogs of pentamidine (including I), 7 primary metabolites of pentamidine, and 30 dicationic substituted bisbenzimidazoles were screened for their inhibitory and fungicidal activities against Candida albicans and Cryptococcus neoformans. A majority of the compounds had MICs at which 80% of the strains were inhibited (MIC80s) comparable to those of amphotericin B and fluconazole. Unlike fluconazole, many of these compounds, such as II and III, were found to have potent fungicidal activity. The most potent compound against C. albicans had an MIC80 of ≤0.09 μg/mL, and the most potent compound against C. neoformans had an MIC80 of 0.19 μg/mL. Selected compounds, such as IV, were also found to be active against Aspergillus fumigatus, Fusarium solani, Candida species other than C. albicans, and fluconazole-resistant strains of C. albicans and C. neoformans. It is clear from the data presented here that further studies on the structure-activity relationships, mechanisms of action and toxicities, and in vivo efficacies of these compounds are warranted to determine their clin. potential. In the experiment, the researchers used many compounds, for example, 1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6Recommanded Product: 1-(5-Bromobenzofuran-2-yl)ethanone).

1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6) belongs to benzofurans derivatives.Benzofuran is one of the most significant oxygen-containing heterocycles consisting of fused benzene and furan ring, which are widely presented in various naturally occurring and synthetically active compounds. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.Recommanded Product: 1-(5-Bromobenzofuran-2-yl)ethanone

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem