Electric Literature of 54008-77-4, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 54008-77-4, 2-Bromobenzofuran, introducing its new discovery.
In a recent study, we investigated the antimicrobial activity of a collection of resveratrol-derived monomers and dimers against a series of foodborne pathogens. Out of the tested molecules, dehydro-delta-viniferin and dehydro-epsilon-viniferin emerged as the most promising derivatives. To define the structural elements essential to the antimicrobial activity against the foodborne pathogen L. monocytogenes Scott A as a model Gram-positive microorganism, the synthesis of a series of simplified benzofuran-containing derivatives was carried out. The systematic removal of the aromatic moieties of the parent molecules allowed a deeper insight into the most relevant structural features affecting the activity. While the overall structure of compound 1 could not be altered without a substantial loss of antimicrobial activity, the structural simplification of compound 2 (minimal inhibitory concentration (MIC) 16 mumug/mL, minimal bactericidal concentration (MBC) >512 mumug/mL) led to the analogue 7 with increased activity (MIC 8 mumug/mL, MBC 64 mumug/mL).
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Electric Literature of 54008-77-4. In my other articles, you can also check out more blogs about 54008-77-4
Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3218O – PubChem