Electric Literature of 16859-59-9, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 16859-59-9, 3-Hydroxyisobenzofuran-1(3H)-one, introducing its new discovery.
Rational design of inhibitors of VirA-VirG two-component signal transduction
VirA-VirG two-component system regulates the vir (virulence) operon in response to specific host factors (xenognosins) in the plant pathogen Agrobacterium tumefaciens. Using whole cell assays, stable inhibitors inspired by the labile natural benzoxazinone inhibitor HDMBOA are developed. It is found that aromatic aldehydes represent a minimal structural unit for activity. In particular, 3-hydroxy-4,6-dimethoxy-3H-isobenzofuran-1-one (HDI) was found to have the highest activity, making it the most potent developed inhibitor of virulence gene expression in Agrobacterium.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Electric Literature of 16859-59-9. In my other articles, you can also check out more blogs about 16859-59-9
Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H1479O – PubChem