Benzofuran · Research Notes

Benzofuran

分子骨架、合成化学与生物活性

Benzofuran 是由苯环与呋喃环稠合而成的含氧杂环骨架。其紧凑的结构、可修饰的反应位点与广泛的生物活性,使其成为药物化学、杂环合成与功能材料研究中的重要平台。本网站以研究笔记的形式,梳理该骨架的合成策略、反应化学与生物学意义。

Peer-reviewed sources · Updated 2026
Benzofuran molecular structure
Benzofuran · C₈H₆O
Latest Literature

最新文献

Research Note
2023.01.06

Xue, Christine et al. published their research in Royal Society Open Science in 2017 | CAS: 38183-12-9

4-Phenyl-3H,3'H-spiro[furan-2,1'-isobenzofuran]-3,3'-dione (cas: 38183-12-9) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Formula: C17H10O4

Research Note
2023.01.06

Suga, Takuya et al. published their research in Chemical Communications (Cambridge, United Kingdom) in 2014 | CAS: 1646-27-1

Methyl benzofuran-2-carboxylate (cas: 1646-27-1) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Electric Literature of C10H8O3

Research Note
2023.01.06

Kawase, Yoshiyuki et al. published their research in Bulletin of the Chemical Society of Japan in 1974 | CAS: 1646-27-1

Methyl benzofuran-2-carboxylate (cas: 1646-27-1) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.HPLC of…

Research Areas

研究方向

围绕苯并呋喃骨架,从分子构建、反应机制到生物功能与材料应用,形成四个相互连接的研究主题。

药物合成
01

药物合成

从经典环化到过渡金属催化与绿色合成路线,探索苯并呋喃骨架的高效构建。

杂环化学
02

杂环化学

关注芳香性、反应位点与稠合或螺环修饰,理解含氧杂环的反应性与选择性。

生物活性
03

生物活性

梳理抗菌、抗肿瘤、抗炎与抗氧化活性,讨论构效关系与潜在作用靶点。

材料应用
04

材料应用

探索苯并呋喃衍生物在有机光电、荧光探针与功能材料中的结构—性能关系。