Quality Control of Isobenzofuran-1(3H)-one. Recently I am researching about ENDOTHELIAL-CELLS; OXIDATIVE STRESS; SENKYUNOLIDE I; Z-LIGUSTILIDE; CHUANXIONG; INJURY; STROKE, Saw an article supported by the Shanghai Municipal Commission of Health and Family Planning [ZY3-CCCX-3-5001]; Science and Technology Commission of Shanghai MunicipalityScience & Technology Commission of Shanghai Municipality (STCSM) [14401901400, 15DZ2292000]; Expenditure Budget Program of Shanghai Municipal Education Commission [2016YSN24]; Xinglin Young Talent Program of Shanghai University of Traditional Chinese Medicine. Published in TAYLOR & FRANCIS LTD in ABINGDON ,Authors: Fang, X; Ma, Q; Zhang, KX; Yao, SY; Feng, Y; Jin, YS; Liang, S. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one
As part of our continuing efforts to discover structurally interesting bioactive phthalide derivatives, 23 of them with a structure incorporating thiophen or halogens were designed and synthesized, 17 of which are previously unreported. In vitro antiplatelet aggregation activity screening showed that 14b could significantly inhibit platelet aggregation induced by arachidonic acid, compared with edaravone (p < 0.01). Meanwhile, oxidative damage models using SH-SY5Y and PC12 cells induced by H2O2 were built to evaluate the antioxidant activity of the phthalide derivatives. In SH-SY5Y cells, compared with aspirin, 1a significantly increased the relative cell survival rate (p < 0.05). Compared with edaravone, 1a (p < 0.01) and 15b (p < 0.05) significantly increased the relative cell survival rate. In PC12 cells, 1a (p < 0.01), 15b (p < 0.01), and 12a (p < 0.05) remarkably increased the cell survival rate compared with edaravone. The present study identified lead structures to develop potential anti-ischemic stroke agents. Quality Control of Isobenzofuran-1(3H)-one. Bye, fridends, I hope you can learn more about C8H6O2, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem