Recently I am researching about FRIEDEL-CRAFTS ALKYLATION; CYCLIZATION; HALIDES; ARENES; ACID; NUCLEOPHILES; ALCOHOLS; BROMIDES, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21703061]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Lv, F; Xiao, J; Xiang, JC; Guo, FZ; Tang, ZL; Han, LB. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one. Computed Properties of C8H6O2
For the first time, H3PO3 was used as both the reducing reagent and the promotor in the reductive benzylation reactions with aryl aldehydes. By using a H3PO3/I-2 combination, various aromatic aldehydes underwent iodination reactions and Friedel-Crafts type reactions with arenes via benzyl iodide intermediates, readily producing benzyl iodides and diarylmethanes in good yields. Intramolecular cyclization reactions also took place, giving the corresponding cyclic compounds. This new strategy features easy-handling, low-cost, and metal-free conditions.
About Isobenzofuran-1(3H)-one, If you have any questions, you can contact Lv, F; Xiao, J; Xiang, JC; Guo, FZ; Tang, ZL; Han, LB or concate me.. Computed Properties of C8H6O2
Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem