Tag: M.W=400-450

He, Xingcun published the artcileCatalytic determination of osmium by using flow-injection analysis, Safety of 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, the publication is Huaxue Tongbao (1988), 41-2, database is CAplus.

Os(VIII) was determined by flow-injection spectrophotometry (monitored at 640 nm) based on the catalytic effect of Os(VIII) on the decolorization reaction of α-naphtholphthalein and KIO₄ in borate buffer solution at pH 9.20-9.80. The catalytic reaction is a zero-order reaction. The calibration curve is linear for 0.010-0.12 μg Os/mL. The detection limit is 0.010 μg/mL. The method is accurate, simple, and with an anal. rate of 75/h. Os was determined in ore concentrates and slags with satisfactory results.

Huaxue Tongbao published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Safety of 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Meier, Michael A. R. published the artcileStatistical Approach To Understand MALDI-TOFMS Matrices: Discovery and Evaluation of New MALDI Matrices, Related Products of benzofurans, the publication is Analytical Chemistry (2007), 79(3), 863-869, database is CAplus and MEDLINE.

A statistical approach is described to better understand the role of the matrix during a MALDI-TOFMS experiment Potential matrix mols. were selected based on a rational exptl. design and subsequently screened in order to investigate whether a certain compound can act as a matrix for synthetic polymers. The tested compounds were selected from a pool of 11 000 mols. based on descriptor calculations and a subsequent D-optimal design selection procedure. This approach selected 59 organic compounds that were then investigated for their ability to act a matrix for synthetic polymers in MALDI-TOFMS experiments Within this contribution, we focus on the discussion of new MALDI-TOFMS matrixes that were discovered in the course of the screening. At least 10 new matrixes were identified, and 5 of these were subsequently tested more closely with a variety of different synthetic polymers of different mol. weights revealing good to excellent performance of these new matrixes.

Analytical Chemistry published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Related Products of benzofurans.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Ghoneim, Mohamed M. published the artcilePolarographic reduction of phenolphthalein, cresolphthalein, thymolphthalein, and α-naphtholphthalein in aqueous and nonaqueous ethanolic solutions, Name: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, the publication is Canadian Journal of Chemistry (1979), 57(11), 1294-8, database is CAplus.

The polarog. reduction of phenolphthalein, cresolphthalein, thymolphthalein, and α-naphtholphthalein was studied in ethanolic Britton-Robinson buffer series (pH 2-12), nonaqueous ethanolic medium, and aqueous EtOH. The compounds are reduced through a single 2-electron wave in nonaqueous medium, and aqueous buffered solutions of pH <9 or 1-electron steps for pH >9. The nature of the waves, mechanism of the electrode reaction, and kinetic parameters are considered.

Canadian Journal of Chemistry published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Name: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Dring, Ann M. published the artcileRational quantitative structure-activity relationship (RQSAR) screen for PXR and CAR isoform-specific nuclear receptor ligands, Formula: C28H18O4, the publication is Chemico-Biological Interactions (2010), 188(3), 512-525, database is CAplus and MEDLINE.

Constitutive androstane receptor (CAR) and pregnane X receptor (PXR) are closely related orphan nuclear receptor proteins that share several ligands and target overlapping sets of genes involved in homeostasis and all phases of drug metabolism CAR and PXR are involved in the development of certain diseases, including diabetes, metabolic syndrome and obesity. Ligand screens for these receptors so far have typically focused on steroid hormone analogs with pharmacophore-based approaches, only to find relatively few new hits. Multiple CAR isoforms have been detected in human liver, with the most abundant being the constitutively active reference, CAR1, and the ligand-dependent isoform CAR3. It has been assumed that any compound that binds CAR1 should also activate CAR3, and so CAR3 can be used as a ligand-activated surrogate for CAR1 studies. The possibility of CAR3-specific ligands has not, so far, been addressed. To investigate the differences between CAR1, CAR3 and PXR, and to look for more CAR ligands that may be of use in quant. structure-activity relationship (QSAR) studies, we performed a luciferase transactivation assay screen of 60 mostly non-steroid compounds Known active compounds with different core chemistries were chosen as starting points and structural variants were rationally selected for screening. Distinct differences in agonist vs. inverse agonist/antagonist effects were seen in 49 compounds that had some ligand effect on at least one receptor and 18 that had effects on all three receptors; eight were CAR1 ligands only, three were CAR3 only ligands and four affected PXR only. This work provides evidence for new CAR ligands, some of which have CAR3-specific effects, and provides observational data on CAR and PXR ligands with which to inform in silico strategies. Compounds that demonstrated unique activity on any one receptor are potentially valuable diagnostic tools for the investigation of in vivo mol. targets.

Chemico-Biological Interactions published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Formula: C28H18O4.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Nakamura, Naoki published the artcileThe response characteristic of optical carbon dioxide sensor using pH indicator immobilized in ethyl cellulose film, Computed Properties of 596-01-0, the publication is Transactions of the Materials Research Society of Japan (2004), 29(3), 923-926, database is CAplus.

A new optical CO₂ sensor based on the overlay of the CO₂ induced absorbance change of pH indicator α-naphtholphthalein with fluorescence of tetraphenylporphine (TPP) was developed and its CO₂ sensing characteristics were studied. The observed fluorescence intensity from TPP at 655 nm increased with increasing CO₂ concentration The I₁₀₀/I₀ value that shows the sensitivity of sensor containing 13.4 mmol dm^-3 α-naphtholphthalein concentration is estimated to be 168, where I₀ and I₁₀₀ represent observed fluorescence intensities from a film exposed to argon and CO₂ saturated condition, resp. The response time of the sensing film containing 13.4 mmol dm^-3 α-naphtholphthalein concentration was 3.8 s for switching from argon to CO₂ and the recovery time of the sensing film also was 6.8 s for switching from CO₂ to argon.

Transactions of the Materials Research Society of Japan published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Computed Properties of 596-01-0.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Ramart, Pauline published the artcileMolecular transpositions in the α,α,α-alkyldiarylethanol series, Synthetic Route of 596-01-0, the publication is Compt. rend. (1926), 1342-4, database is CAplus.

It has already been shown (cf. C. A. 19, 645) that by dehydration of primary alkyldiaryl alcs., transposition of the aryl radical occurs when the hydrocarbon is formed. In a further study of this dehydration and transposition the following alcs. were prepared, the 1st being unknown heretofore. 2,2,3-Triphenylpropanol, Ph₂(PhCH₂)CCH₂OH, from benzyl diphenylbenzylacetate and Na in absolute EtOH, m. 80°, b₁₆ 240°; phenylurethan, m. 169°; Bz derivative, m. 95°. (PhCH₂)₂PhCOH, by condensation of BzMgCl with desoxybenzoin. Ph₂(PhCH₂CH₂)COH, from PhMgBr and PhCH₂CH₂CO₂Et. Dehydration of Ph₂(PhCH₂)CCH₂OH with P₂O₂ gave a mixture of Ph₂C:CHCH₂Ph and Ph(PhCH₂)C:CHPh, the latter predominating.

Compt. rend. published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Synthetic Route of 596-01-0.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Fernandez-Ramos, M. D. published the artcileIonic liquids on optical sensors for gaseous carbon dioxide, Application In Synthesis of 596-01-0, the publication is Analytical and Bioanalytical Chemistry (2018), 410(23), 5931-5939, database is CAplus and MEDLINE.

This work presents a study on the influence of eight different ionic liquids (ILs) in the composition of dry membranes used for gaseous CO₂ optical sensing. The presence of CO₂ causes a displacement of a colorimetric pH indicator toward its acid form that increases the emission intensity of the luminophore by an inner filter process. The influence of ILs in the membrane on the stability and dynamic behavior-usually the main drawbacks of these sensors-of the membranes was studied. The characterization of the different membranes prepared was carried out and the discussion of the results is presented. In all cases, the response and recovery times improved considerably, with the best case being response times of only 10 s and recovery times of 48 s, compared to response and recovery times of 41 and 100 s, resp., for membranes without IL. The useful life of the detection membranes is also considerably longer than that of membranes that do not include IL, at least 292 days in the best case. The sensing membrane without luminophore and only containing the pH indicator is proposed for the color-based measurement of CO₂ using a digital camera for possible use in food-packaging technol. [Figure not available: see fulltext.].

Analytical and Bioanalytical Chemistry published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Application In Synthesis of 596-01-0.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem