79002-39-4, Benzofuran-5-carbonitrile is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,79002-39-4
EXAMPLE 15:PREPARATION OF 5-(5-FORMYL-I -BENZOFURAN-2-YL)-6-METHYL-4-[(4- METHYL-1 H-INDOL-5-YL)AMINO]NICOTINONITRILEStep a): Preparation of 5-formylbenzofuran.To a -150C to -2O0C solution of 1-benzofuran-5-carbonitrile (5 g, 34.9 mmol) in 50 mL of dichloromethane under nitrogen was added DIBAL-H (41.9 mL, 41.9 mmol, 1.0M in heptane) such that the temperature was less than or equal to -150C. The reaction mixture was stirred for an additional 10 min at -150C to -2O0C and quenched by adding 2.0 N HCI dropwise such that the temperature was less than or equal to room temperature. The organic layer was then separated, washed with water, dried over sodium sulfate and concentrated to give 4 g (78%) of the title compound as a yellow oil, which was used in the next step without further purification.
79002-39-4 Benzofuran-5-carbonitrile 2795184, abenzofuran compound, is more and more widely used in various fields.
Reference£º
Patent; WYETH; WO2009/76571; (2009); A1;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem