652-39-1, 4-Fluoroisobenzofuran-1,3-dione is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
652-39-1, A mixture of 3 -fluorophthalic anhydride (1 equiv.), 9-amino-S -(4-methoxybenzyl)-2-oxa- 6-thia-5-azaspiro[3.5]nonane 6,6-dioxide (1 equiv.), and potassium acetate (2.5 equiv.) in acetic acid is stirred at 120 ¡ãC overnight. The dark mixture is cooled and filtered. The filter cake is dissolved in DCM and washed with saturated NaHCO3 and brine. The organic layer is dried (Na2 SO4) and concentrated to provide 4-fluoro-2? -oxetano-6? -sulfonyl-thalidomide.
As the paragraph descriping shows that 652-39-1 is playing an increasingly important role.
Reference£º
Patent; C4 THERAPEUTICS, INC.; PHILLIPS, Andrew, J.; NASVESCHUK, Chris, G.; HENDERSON, James, A.; LIANG, Yanke; FITZGERALD, Mark, E.; MICHAEL, Ryan, E.; (790 pag.)WO2017/197056; (2017); A1;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem