A study on bio implants materials and machining was written by Sivakumar, S.;Adam Khan, M.;Ebenezer, G.;Chellaganesh, D.. And the article was included in Materials Today: Proceedings in 2021.Category: benzofurans This article mentions the following:
In current scenario, the engineering materials are profound their application towards Bio-Medical field. The human implants caught the eye of researchers in the field of materials and metallurgy. After meeting the accidents, aged people’s bone crack, and other factors for replacing bones is a major problem faced by the medical society. Considering the fact, researchers have found some viable alternative for the bone material which are pos. towards biocompatibility. Now-a-days the human implants are available com. but for particular length, and the implants are not patient specific. To overcome the current issue, machining the materials have been using as the conventional methods to make them into patients’ specific implants. While machining the implants, complex shapes cannot be machined by traditional approach, on the other hand, the biocompatibility of the material have been spoiled. In the com. market both stainless steel and the titanium-based implants play a vital role in the replacement of the bone. The com. grade of titanium implant is not pure titanium but the alloy of titanium. Due to the lack of biocompatibility the machined implant material cannot resist the bio-corrosion, eventually, it leads to the lack in the growth of the human cells. Usually the implants are placed in the human body, which is in contact with the live tissue containing the fibroblast cells (Skin cells). Lack of biocompatibility of the human implants reflects on the growth of the fibroblast cells, healing the surgery wound, further it may also lead to allergy to the patient. In the experiment, the researchers used many compounds, for example, Sodium 2′,4′,5′,7′-tetraiodo-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-bis(olate) (cas: 16423-68-0Category: benzofurans).
Sodium 2′,4′,5′,7′-tetraiodo-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-3′,6′-bis(olate) (cas: 16423-68-0) belongs to benzofurans derivatives. Benzofuran derivatives have shown many biological activities, including antifungal and antimicrobial properties, and acting as antagonists of H3 receptors and angiotensin II. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Category: benzofurans
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem